...210.com 关键词】 肝硬化,胆汁性;自身抗原;重组融合蛋白质类 [gap=1387]Key words] liver cirrhosis,biliary;autoantigens;recombinant fusion proteins ...
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Concerning about specific autoantigens, experiments demonstrated that most autoantibodies were against the thyroglobulin, thyroid peroxidase and TSH receptor which existed in thyroid tissues, thyroid stimulating Abs(TSAb) or thyroid stimulating immunoglobulin(TSI) were the main autoantibodies found.
大量实验研究已证实甲状腺组织存在特有的自身抗原成分,目前已了解的主要有甲状腺球蛋白(Tg)、甲状腺过氧化物酶(TPO)、促甲状腺激素受体(TSHR),所产生的抗体主要是甲状腺刺激性抗体(TSAb)或甲状腺刺激免疫球蛋白(TSI)。
参考来源 - Graves病的免疫分子致病机制的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
Oral tolerance by feeding autoantigens is an effective method to prevent EAE and to treat MS, which mechanism has not been made very clear.
小剂量口服自身抗原诱导免疫耐受可有效地抑制EAE和MS,这已被诸多研究所证实,但其机制尚不清楚。
Preabsorption and binding assays indicated the existence of cross-reactive epitopes on SARS-CoV spike protein domain 2 (S2). Several candidate autoantigens have been identified.
竞争结合的实验分析指出SARS冠状病毒棘蛋白区域2 (S2) 确实有交互作用的抗原决定位存在,进一步的实验鑑定出数个自体抗原。
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