The drug - called an Aurora kinase inhibitor - improved survival for mice when combined with chemotherapy.

该药物称为极光激酶抑制剂-改善小鼠化疗时候的存活率。

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Both the structures and the functions of aurora kinase family members are highly conserved in different model organisms.

在不同的模式生物中，极光激酶各家族成员的结构和功能都高度保守。

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The invention also includes pharmaceutical compositions, including the compounds, and methods of treating disease states related to the activity of Aurora kinase.

本发明还包括所述化合物的药用组合物以及治疗与蛋白激酶的活性相关的疾病状态的方法。

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