Phosphorylation of Aurora A at Thr288 in its catalytic domain increases kinase activity.

极光激酶A催化结构域苏氨酸（288位）的磷酸化能够增强激酶的活性。

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Aurora A (AIK) is a cell cycle-regulated serine/threonine protein kinase that is overexpressed in many tumor cell lines (1-3).

极光激酶A（AIK）是一种调节细胞周期的丝氨酸/苏氨酸蛋白激酶，在多种肿瘤细胞系中过表达（1-3）。

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