TGFβ1 and HGF could respectively promote and inhibit proliferation of atrial fibroblast;expression of CTGF,α-SMA; secretion of collagen I ,MMP-2;and atrial fibrosis.
TGFβ1和HGF分别通过促进和抑制心房成纤维细胞增殖,上调和下调细胞CTGF、α-SMA表达及胶原和MMP-2分泌,促进和抑制心房纤维化。
参考来源 - HGF/TGFβ1在风湿性心脏病心房颤动患者心房纤维化的作用机制研究·2,447,543篇论文数据，部分数据来源于NoteExpress
Imidapril inhibit atrial fibrosis maybe also related to affect the CTGF way.
咪达普利抑制心房纤维化可能还与影响CTGF途径有关。
Benazepril and valsartan can decreased the degree of atrial fibrosis and remodeling of Gap junction connexin effectively.
贝那普利及缬沙坦可有效减轻心房纤维化和心肌缝隙连接蛋白的重构。
Fibrosis of atrial myocytes may be involved in the occurrence and maintenance of AF.
心房肌的纤维化与房颤的发生及维持有关。
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