Methods: APP transgenic mice of same age and APP positive control (divided in groups of difference by dosage) were selected to perform water maze and jump platform experiments.
方法:选用同龄转基因APP阳性动物(不同用药组)做水迷宫和跳台实验。
CONCLUSION: HNYCF evidently ameliorates the learning and memory ability in APP transgenic mice, which may be related to the anti-inflammatory and anti-oxidation effects of HNYCF.
结论:HNYCF可以改善APP转基因小鼠的学习记忆能力,其作用机制可能与抗炎、抗氧化作用有关。
It is proved that the conformity site of exogenous gene in APP transgenic mice is random, the tumor induced by gene conformity site could manifest with different stage of cell growing.
结论证实了转基因动物导入外源性基因整合位点是随机的;整合位点引起的肿瘤可以随着细胞发育的不同阶段,逐渐的显现。
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