Objective To investigate the impact of non target gene mutations and reduced permeability of the outer membrane on quinolone resistance and multiple antibiotic resistance (mar) in Escherichia coli.

目的：探讨非靶位基因突变及外膜通透性改变对大肠杆菌喹诺酮类耐药和多重耐药的影响。

youdao

Generally, antibiotic resistance is spread through a process called horizontal gene transfer, the simple passing of genes from one individual to another.

一般来说，抗生素抗性的传播是通过一个叫做水平基因转移的过程实现的，就是基因从一个个体转移到另一个个体的过程。

youdao

If your gene goes in, you've interrupted the gene for antibiotic resistance and those new organisms aren't going to be resistant to antibiotic anymore.

如果基因进入了质粒,原本对抗生素有抗性的基因就被打断了,那些新细菌就不再对抗生素有抗性

耶鲁公开课 - 生物医学工程探索课程节选

One way that you can look for that gene that you want is by making the cut in your plasmid inside of a gene that encodes for some property like resistance to an antibiotic.

一种找到成功重组质粒的方式,是在质粒控制某种特性的编码区域切割,例如,对抗生素的抗性

耶鲁公开课 - 生物医学工程探索课程节选

The discovery that animals in pristine environments have few bacteria with resistance genes makes it likely that much of the antibiotic resistance found in these other species is a result of human influence, rather than natural gene-circulation.

ECONOMIST: Are the bugs in wild animals resistant to antibiotics?