You will need all of your work space free from clutter.

你工作的空间不能乱糟糟的。

youdao

All of your work will be saved, even if you leave the application.

您的所有工作都要保存，即使您停止了这个应用软件。

youdao

However, this will replace all of your work in this project, so backup anything you want to keep.

不过，这将替换您在此项目中的所有工作，所以，请备份您需要保存的任何内容。

youdao

All the work of the organization will be your responsibility.

VOA: special.2009.12.13

You can very quickly drive yourself nuts by sitting down, thinking, oh, I can write this program, no sweat, and then you write it and then there's a tiny little mistake here, but then there's a tiny little mistake here and here, and all of these stupid little things cascade until you try running your program, and the thing just doesn't work.

如果你只是仅仅干坐着，不费吹灰之力，凭空幻想着我可以把这个项目搞定，你会想地发疯的，也许你会写出一点东西出来，可能会有一点点错误,紧接着这或那又出现一点小错误，这些小错误一点一点地堆积了起来,直到你开始运行你整个项目，你会发现这堆东西根本就不工作。

哈佛公开课 - 计算机科学课程节选

Definitely not worth all of your work and patience.

WSJ: Mom-and-Pop Pulled Pork

You may be funny, smart and easy to dance with, but if you are not engaging employees on an ongoing basis, all of your work in developing a strategic plan will be for naught.

FORBES: Why Engaging Your Employees Is The Answer To Strategic Planning

So the subtle message is that you should take vacation but also make sure that you get all of your work done, and meet your goals without sloughing off your assignments to anyone else.

FORBES: Take Your Vacation -- Please!