The period known as adolescence is a significant time of change for the individual experiencing it.

青少年时期是对于经历过它的个体的改变来说是一个重要时期。

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The postponement of the Mediaroom conference comes at a significant time for the Microsoft IPTV team and product/service.

然而该会议的推迟也可能和微软其他的电视服务/产品有关。

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While those duties do not constitute a significant time commitment, they do reflect the CLASP philosophy that effective security practices require organizational buy-in.

虽然这些职责没有组成一个及其重要的时间承诺，他们反映了CLASP哲学，即有效的安全性实践需要组织极的买入。

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But politics is (takes) a long, long time to make any significant, long-lasting difference."

VOA: special.2010.05.09

"Whether or not they blame Karzai for that personally, I think that there is a general sense among significant parts of the population that it may be time for a change.

VOA: standard.2009.08.03

The G20,which includes major industrialized powers in the Group of Eight plus developing nations with significant economies such as China and India, agreed to a specific time line for deficit reduction, while giving governments flexibility to adjust the pace of changes based on their own situations.

VOA: standard.2010.06.27

She said alternative sources had "known weaknesses including gaps, double counting and a significant time lag".

BBC: Census 'should be scrapped now'

For me, the point here is that it takes a significant time commitment to make any sort of breakthrough when working on ambiguous questions.

FORBES: The Frustration of Diversity

In addition to the 90 days that the bank spends mentoring several participants each vendor usually works with two to three banks five additional weeks go into candidate selection, program preparation and follow-up a significant time commitment for the bank executives.

FORBES: New York's FinTech Innovation Lab Links Startups To Big Banks