Lawlessness is a major problem.

违反法律是一个严重的问题。

《柯林斯英汉双解大词典》

Stress is a major problem of modern life.

压力是现代生活中的主要问题。

《牛津词典》

Drug abuse has long been a major problem for the authorities there.

毒品滥用长期以来一直是那里的当局的一大难题。

《柯林斯英汉双解大词典》

The report says overfishing is a major problem that government rules have done little to stop.

VOA: special.2010.05.25

So, many people have relatives they know of that have had to have their heart imaged -- heart disease is a major problem in the United States, and there's a good chance that they had Cardiolite given to them to help in that imaging process.

它被用在心脏成像中,很多人都有一些亲戚他们-,必须要做心脏成像，心脏病已经是美国的一个主要问题,而很有可能他们就要用到Cardiolite来成像。

麻省理工公开课 - 化学原理课程节选

This solves a major problem which I'm going to talk about just at the beginning of class here in a slide or two, is how to get DNA into cells?

这解决了我要讲到的一个主要问题,就是在这节开始的一两张幻灯片中要讲的,怎样将DNA导入细胞的问题

耶鲁公开课 - 生物医学工程探索课程节选

We could have a major problem, I think, either this summer or the next couple years.

FORBES: Wall Street 'Vastly Underestimating' Risk of Debt Default

And while the device is silly-looking, it does address a major market and a major problem.

FORBES: Magazine Article

One of the big Belfast dealerships said these older vehicles now represent a major problem.

BBC: Credit crunch hits NI motor market