It will be a devastating blow to the local community if the factory closes.

如果这家工厂倒闭，将给当地居民以毁灭性的打击。

《牛津词典》

It's gonna end up, you know, being a devastating blow to the middle class here.

这会结束，你知道，对在这里的中产阶级是毁灭性的打击。

youdao

In a race where every second matters, it was a devastating blow to Armstrong's hopes of winning a record eighth Tour DE France.

比赛中可谓分秒必争，这对于想获得第八次环法冠军的阿姆斯特朗来说是个毁灭性的打击。

youdao

Japanese industries would suffer a devastating blow were Japan not to be a party to this agreement.

FORBES: Yomiuri's New Year's Editorial

The co-conspirators agreed to a pension termination that served them well but dealt a devastating blow to UAL employees.

FORBES: PBGC Pension Termination: A Worker's Perspective by Terry O'Rourke, United airlines (December 15, 2007 )

His side were also dealt a devastating blow at half-time with defender Conor McLaughlin suffering a suspected broken leg.

BBC: Sport - Football - Preston 0-4 Bristol City