...致机体缺乏叶酸有两个方面的原因，一是叶酸摄入量不足；二是与叶酸代谢相关的基因发生异常。5,10-亚甲基四氢叶酸还原酶（MTHFR）和甲硫氨酸合成酶还原酶（MTRR）是参与叶酸代谢的最重要的两个酶，当编码这两个酶的基因发生突变时，会引起叶酸代谢异常。
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Anti- MTHFR 亚甲基四氢叶酸还原酶MTHFR抗体
MTHFR gene MTHFR基因
MTHFR基因 MTHFR gene
MTHFR polymorphism MTHFR多态性
MTHFR Gene C677T Mutation MTHFR基因C677T突变
methylenetetrahydrofolate reductase MTHFR 亚甲基四氢叶酸还原酶
Variants of MTHFR, for example, have been linked to increased risk of cardiovascular disease.
例如，MTHFR的变异体被认为能增加心血管病的风险。
This study was to evaluate the effect of MTHFR C677T polymorphism on chemosensitivity and toxicity to 5 FU in patients with gastric carcinoma.
本研究旨在观察mthfr基因C677T多态性对预测胃癌患者对5 - FU的敏感性和化疗毒性的影响。
Conclusions the C677T mutant frequency of MTHFR might be correlated only with cerebral infarction but not with the frequency of onset of cerebral infarction.
结论MTHFR基因C677T突变可能与脑梗死的发病有关，但与脑梗死发病的次数无关。
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