Long-term treatment with the second-generation nucleoside analogue lamivudine (lam) efficiently inhibits HBV replication with frequent viral polymerase mutations.
二代拉米夫定的长期应用可以有效地抑制病毒多聚酶突变频繁的HBV发生复制。
Objective:To observe the efficacy and safety of adefovir dipivoxil(ADV)for chronic hepatitis B(CHB)with YMDD mutation during lamivudine(LAM)therapy.
目的 系统评价与拉米夫定相关的乙型肝炎病毒YMDD区变异后不同抗病毒治疗方法的疗效和安全性。
应用推荐