除阻滞T型和L型钙通道,咪拉地尔还能够抑制延迟整流钾电流(IK)、钠通道电流(INa)和细胞色素P450。有学者提出,咪拉地尔防止心房电重构可能是通过抑制细胞色素P450。
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Results (1). Garlicin could decrease the sodium channel current in a dose-dependent and voltage-dependent manner.
结果(1).快钠通道电流:大蒜素对豚鼠心室肌细胞I_(Na)呈电压依赖性和浓度依赖的抑制作用。
参考来源 - 大蒜素对心室肌细胞膜钠通道电流影响的研究·2,447,543篇论文数据,部分数据来源于NoteExpress
方法:采用全细胞膜片钳技术,记录钠通道电流。
Methods: Whole-cell patch clamp technique was used to determine sodium channel cur rent.
目的:研究血竭对大鼠背根神经节细胞电压门控性钠通道电流的影响。
Objective: to investigate the effects of blood resin on voltage gated sodium channel current in freshly isolated rat DRG neurons.
方法用急性酶解法获得单个大鼠心室肌细胞,标准的全细胞膜片钳技术记录钠通道电流。
The whole-cell patch-clamp recording technique was used to record the change of sodium channel current influenced by carvedilol.
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