高风险状态包括:哮喘,镰状红细胞贫血,艾滋病毒感染,慢性心脏疾病,等等。
High risk conditions included asthma, sickle cell disease, HIV infection, and chronic cardiac disease, among others.
随着镰珠蛋白中氧的去除,红细胞变形成镰状,红细胞膜受到破坏,破裂的可能性增加,从而导致贫血。
With the removal of oxygen from sickle hemoglobin, the red blood cell deforms into a sickled shape. This sickling damages the RBC membrane and increases the likelihood of rupture and anemia.
It's a single gene defect and we know exactly where the genetic defect is in sickle cell.
是一种单基因缺陷,而且我们准确地知道,镰状红细胞贫血的基因缺陷在哪里
It's on the gene for hemoglobin and the hemoglobin that you produce if you have sickle cell anemia is not quite right because there's one base difference.
这个缺陷基因和血红蛋白有关,如果你有镰状红细胞贫血症,那你所产生的血红蛋白就不太正常,因为这里有一个碱基不同
Sickle cell anemia is a disease that affects a subset of the population.
镰状红细胞贫血症,是一种作用于特定人群的疾病
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