...新的NF-κB 功能性(functional)结合靶点和靶基因,构建NF-κB 控制的基因转录调控网络(transcriptional regulatory network),描绘NF-κB 的完整生物学全貌,为NF-κB的生物医学应用提供科学依据。
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因此识别转录因子结合位点成为构建转录调控网络的第一步。
Transcription regulation proteins must bind to these sequences in order to regulate the transcription of the gene.
尽管荚膜的患病率及其对人体健康的威胁,我们有一个有限的转录调控网络的认识,管理致病酵母相生长。
Despite the prevalence of h. capsulatum and its threat to human health, we have a limited understanding of the transcriptional regulatory network that governs pathogenic yeast-phase growth.
作为转录因子的STAT 3参与很多基因的表达和调控,并与其他转录因子形成复杂的调控网络。
As a transcription factor, STAT3 participated in the control of their target genes' expression and forms a complicated network together with other transcription factors.
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