目的：探讨特应性皮炎(ad)皮肤生理改变(包括表皮水分丢失量和角质层水分含量)是否与表皮脂的代谢有关。

Objective: to elucidate whether the skin physiology changes including transepidermal water loss (TEWL) and skin hydration in atopic dermatitis (AD) related to abnormal epidermal lipid metabolism.

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当表皮屏障功能障碍，真皮和表皮内水分会大量丢失，发生皮肤干燥、鳞屑、瘙痒。

When the epidermal barrier is blocked, water in dermis and epidermis will lose, which results in dry skin and skin scales.

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