在妥泰联用抗癫痫药丙戊酸盐的女性中出生缺陷发生率最高，后者已被许多研究结果和癫痫数据库认定与出生缺陷相关。
The birth defect rate was highest among women who took Topamax in combination with the epilepsy drug valproate, which has been linked to birth defects in numerous studies and epilepsy databases.
应对出版性偏倚的新型方法：对FDA试验注册数据库和相关期刊杂志中有关抗抑郁药的试验进行次要分析。
Novel methods to deal with publication biases: secondary analysis of antidepressant trials in the FDA trial registry database and related journal publications.
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