间质细胞与细胞外基质成分构成的肿瘤微环境对肿瘤细胞的生长、浸润和转移具有重要作用。
Tumor microenvironment is composed of mesenchymal cells and extracellular matrix components, which plays an important role in the growth, invasion and metastasis of tumor cells.
第三，由于肿瘤细胞来源的外泌体可修饰转移前微环境 境[6]，从循环系统中去除这些外泌体可能可以阻止癌症的转移。
Thirdly, considering cancer-cell derived exosome can modify pre-metastasis niches [6], depleting these exosomes from circulation system is a possible option for blocking cancer metastasis.
一旦转移的肿瘤细胞穿过血脑屏障，脑微环境会对肿瘤定植和生长同时发挥抑制和促进作用。
Once disseminate tumor cells pass through the blood-brain barrier, the brain microenvironment could elicit both inhibiting and promoting effects on tumor colonization and outgrowth.
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