现已发现,氧化应激可以改变端粒酶活性,促使端粒酶从细胞核转位到线粒体,因而不能继续维持端粒长度,使细胞端粒缩短。
It has been demonstrated that telomerase activity would be altered upon oxidative stress and excepted from nucleolus to mitochondria as well as telomere shortening.
HBV基因组核转位进入细胞核是HBV在肝细胞内复制的重要环节。
The entry of HBV genome to nuclear is an important step of HBV replication in hepatocytes.
跨膜受体可从膜表面进入细胞核内直接调控细胞的生命活动,但其核转位的途径至今尚无定论。
Although transmembrane receptors from cell surface to nucleus can generally regulate the cellular life activities, their pathways of nuclear translocation still remain to be elucidated.
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