目的：研究阿仑膦酸盐通过凋亡抑制破骨细胞性骨吸收的作用。
Objective: to study the inhibiting effect of alendronate on the apoptosis of osteoclasts.
结论双膦酸盐对破骨细胞性骨吸收有明显的抑制作用。
Conclusions Osteoclast-mediated bone resorption was inhibited by the bisphosphonate administration.
提示APD具有较强的直接抑制破骨细胞性骨吸收的作用，对骨质疏松症可能有一定的疗效。
It is suggested that APD could directly suppress osteoclastic bone resorption and might be effective in osteoporosis.
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