...微注射等方法将打靶载体导入受体细胞内,通过外源载体和内源靶位 点相同的核苷酸序列之间的同源重组(homologous recombination,HR),使外源DNA 定点整合到靶细胞的特定的基因座上。
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减数分裂中的同源重组 Homologous Recombination in Meiosis
为主的同源重组 Homologous recombination
修复进行的同源重组 homologous recombination repair
本发明还涉及人源化改造的基因突变技 术和去除GFP的腺病毒转移载体及去除GFP的同源重组腺病毒载体。
The invention also relates to a human reforming gene mutation technique, adenovirus transition carrier removing GFP and homologous recombinant adenovirus carrier.
这意味着减数分裂中同源染色体不能配对,染色体间形成的交叉也会更少(例如,在减数分裂早期的重组位点)。
This means that homologous chromosomes failed to pair together during meiosis and chromosomes formed fewer crossovers, i. e. sites where they recombine, during the initial stages of meiosis.
更新较缓慢的组织中,似应首选同源重组,因其干细胞不需要种植。
Homologous recombination would presumably be preferred in the case of more slowly-renewing tissues, whose stem cells should not need reseeding.
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