目的:研究天然产物TTS-12对白念珠菌甾醇生物合成途径的影响。
Objective: To study the effect of TTS-12 on the sterol bio-synthetical pathway in Candida albicans.
目的研究抗真菌药物布替萘芬的体外抗真菌活性和对真菌麦角甾醇生物合成的影响。
Objective To study in vitro antifungal activity of butenafine and its effect on ergosterol biosynthesis in fungi.
发现参与麦角甾醇生物合成的甾醇c - 24(28)还原酶基因erg4和甾醇酰基转移酶基因ARE2高表达后,使细胞麦角甾醇含量提高。
Overexpression of sterol C-24 (28) reductase gene ERG4 and sterol acyltransferase gene ARE2 in-creased the ergosterol biosynthesis in yeast cells.
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