Hydrogel patch had themaximum drug concentration in the rat thyroid tissue, next ointment a minimum of oral group.
水凝胶贴剂组大鼠甲状腺组织中的药物浓度最高,软膏组其次,口服组最低。
参考来源 - 甲巯咪唑水凝胶贴剂的研究Objective:The effect of formulation factors on mechanical strength of Viscomate NP-800 based hydrogels and the per-meation enhancing effect of azone and menthol on penetration of indometacin from its hydrogel patch through mice skin were investigated.
目的:探讨影响Viscomate NP-800基水凝胶强度的处方因素以及氮酮和薄荷脑对吲哚美辛水凝胶贴剂中药物透过小鼠皮肤的促透效果。
参考来源 - Viscomate NP·2,447,543篇论文数据，部分数据来源于NoteExpress
水凝胶贴剂组大鼠甲状腺组织中的药物浓度最高，软膏组其次，口服组最低。
Hydrogel patch had the maximum drug concentration in the rat thyroid tissue, next ointment a minimum of oral group.
目的对甲巯咪唑水凝胶贴剂治疗甲状腺功能亢进症(甲亢)的药效学进行研究。
OBJECTIVE To investigate the pharmacodynamics of thiamazole hydrogel patch in rats with hyperthyroidism.
结论：瞬间脉冲电场能够显著提高水凝胶贴剂的透皮给药效果，两者结合将成为一种新型透皮给药技术。
These results suggest that cataplasma to combine with electroporation may be an efficient alternative for transdermal drug delivery of hydrophilic molecules.
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