目的介绍精氨酸甘氨酸天冬氨酸(RGD)肽在肿瘤诊治领域的研究现状、价值及发展前景。
Objective To introduce the current research status, value and development future of Arg-Gly-Asp (RGD) peptides in diagnosis and treatment of neoplasms.
氨基酸组成分析发现活性肽中含有较多的精氨酸、赖氨酸和脯氨酸，同时含较少的谷氨酸和天冬氨酸。
Large quantity of arginine, lysine and proline as well as small amount of glutamic acid and asparagic acid are found in the biological active peptides by amino acid analysis.
由N-保护的精氨酸、C-保护的甘氨酸采用混合酸酐法缩合成RG二肽，再与天冬氨酸在液相中合成RGD三肽。
The RG Dipeptides were condensated from N-protected Arg and C-protected Gly by mixed anhydrides method. Then Asp and RG Dipeptides were synthesized RGD Tripeptides in liquid phase.
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