目的观察曲美他嗪对慢性肾衰竭大鼠左心室重塑的影响及血浆脑钠素(bnp)的变化。

ObjectiveTo observe the effects of trimetazidine (TMZ) on left ventricular remodeling and plasma brain natriuretic peptide (BNP) level in rats with chronic renal failure (CRF).

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本实验采用定量反转录聚合酶链式反应技术，观察大鼠在进行11周中等强度耐力训练过程中心脏心钠素（ANP）和脑钠素（BNP）基因表达的变化。

This study adopted RT-PCR technique to observe the change of express of gene of rats' ANP and BNP during 11 week's moderate intensity endurance training;

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