目的：在慢性间歇缺氧的条件下，用高脂饮食方法建立兔的动脉粥样硬化模型，探讨相关致病机制。
Objective:To establish the rabbit arteriosclerosis mold caused by high-adiposed diet under the condition of chronic intermittent hypoxia, and probe into the correlative mechanism.
结果：在寒冷吸烟慢性支气管炎的病理改变比室温条件下更严重。
Results the pathologic changes of the chronic bronchitis of the mice were more severe under the condition of cold than those under the condition of room temperature.
方法通过石油沥青急性经口毒性、亚慢性吸入毒性及遗传毒性的实验研究，观察在该实验条件下，石油沥青对受试动物的影响。
Methods Acute oral toxicity test, subchronic inhalation toxicity test and mutagenicity test were conducted to observe the effects of petroleum asphalt in experimental animals.
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