血管内皮生长因子(VEGF)是目前所知的作用最强的促血管生成因子之一，它可以直接或间接地参与血管生成的每个环节。

Vascular endothelial growth factor (VEGF) is one of the most powerful pro-angiogenesis factor at present, which can participate in each link of the angiogenesis directly or indirectly.

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还有证据表明，各种基质细胞在正常和病理的血管生成在一个组织或上下文特定的方式参与。

There is also evidence that various stromal cell types participate in normal and pathological angiogenesis in a tissue - or context-specific fashion.

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骨桥蛋白是一种参与炎症、血管生成和转移的糖蛋白，研究发现其在发生癌症转移的病人中血中表达水平较高。

Osteopontin is a glycoprotein involved in inflammation, angiogenesis, and metastasis, and has been found in higher levels in cancer patients with metastatic disease.

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