目的用模拟人卵巢癌抗原并有满意免疫原性的抗独特型微抗体进行临床前动物实验研究。
An anti-idiotypic mini body with optimal antigenicity which mimicking ovarian cancer antigen was used for therapeutic research in mice model bearing ovarian cancer.
为了降低人抗鼠抗体反应,获得满意的免疫原性,将模拟人卵巢癌抗原的抗独特型单链抗体人源化。
In order to reduce the human anti mouse antibody response and obtain optimal antigenicity, anti idiotype single chain which mimicking ovarian cancer antigen has been humanized.
目的评价组织多肽抗原(TPA)在卵巢癌诊断和监测中的临床价值。
Objective to evaluate the clinical usefulness of tissue polypeptide antigen (TPA) in diagnosis and monitoring the course of patients with ovarian carcinoma.
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