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Rogers, 30, replaces Swansea loosehead Darren Morris, with 28-year-old Sinkinson ousting Martyn Williams.
BBC: Henry opts for re-shuffle
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Peter Rogers and Brett Sinkinson will make their debuts for Wales in Saturday's Five Nations clash against France in Paris.
BBC: Henry opts for re-shuffle
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Earlier, two penalties from Neath fly-half Matthew Pearce and a try from former Welsh flanker Brett Sinkinson provided Neath with an early boost.
BBC: Swansea qualify for Europe