但晚期合并骨髓纤维化者则不易与原发性骨髓纤维化相鉴别。
However, combined with advanced myelofibrosis were not easily identify with primary myelofibrosis.
这样的脾肿大通常预示有骨髓增生型疾病，例如慢性髓性白血病或骨髓纤维化。
Such massive splenomegaly is usually indicative of some myeloproliferative disease such as chronic myelogenous leukemia or myelofibrosis.
初期骨髓纤维化的患者容易感觉疲劳，他们有时会服用贫血药来刺激携氧红细胞的生长。
Patients with primary myelofibrosis feel fatigued, and they sometimes take an anemia drug to stimulate growth of oxygen-carrying red blood cells.
骨髓纤维化，骨髓纤维变性在骨髓中成纤维细胞的扩散，常引起贫血症，而且有时也会导致脾和肝的增大。
Proliferation of fibroblastic cells in bone marrow, causing anemia and sometimes enlargement of the spleen and liver.
Nplate的安全性问题包括骨髓纤维化和存在下面状况的可能性，即一旦停用Nplate，血小板计数水平可能跌到最初开始治疗的水平之下。
Safety concerns with Nplate include fibrous deposits in the bone marrow and the possibility that once Nplate is stopped, platelet counts could drop below what they were before beginning treatment.
骨髓的血小板生成量降低可能是由于药物、毒素、或如再生障碍性贫血、肝纤维化、原发性恶性肿瘤或骨髓造血障碍。
Decreased production of platelets in the marrow may be caused by drugs, toxins, or by primary marrow disorders such as aplasia, fibrosis, or hematopoietic malignancy.
结论：骨髓来源干细胞在治疗及预防肺纤维化方面可能存在巨大潜力，其具体治疗方案与治疗机制还有待进一步研究。
CONCLUSION: Bone marrow derived stem cells may have a great potential in the treatment and prevention of lung fibrosis. The particular methods and mechanisms are yet to be investigated.
但肝纤维化本身的慢性病程及病理特征使骨髓干细胞移植的应用具有一定的特殊性。
But there are specificity in treating liver fibrosis by BMSC translation, because of the chronic course and pathologic characteristics of liver fibrosis.
目的探讨骨髓源性肝干细胞（BMDLSC）移植对肝纤维化病变的影响。
Objective To explore the action of transplantation of bone marrow-derived liver stem cells(BMDLSC)on hepatic fibrosis induced by alcohol in mice.
目的探讨骨髓源性肝干细胞（BMDLSC）移植对肝纤维化病变的影响。
Objective To explore the action of transplantation of bone marrow-derived liver stem cells(BMDLSC)on hepatic fibrosis induced by alcohol in mice.
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