目的:研究去氢骆驼蓬碱在体外的杀菌作用。
Objective: Determining the bactericidal effect of harmine in vitro.
目的制备高包封率的盐酸去氢骆驼蓬碱脂质体。
Objective To prepare a harmine hydrochloride liposome formulation with high encapsulation efficiency.
目的:测定盐酸去氢骆驼蓬碱的血浆蛋白结合率。
OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride.
方法:用RP-HPLC法测定不同月份的骆驼蓬不同药用部位中骆驼蓬碱和去氢骆驼蓬碱的含量。
Method: The contents of harmaline and harmine of different parts of Peganum harmala L. collected monthly were determined by RP-HPLC.
目的研究盐酸去氢骆驼蓬碱在大鼠胃肠道各段的吸收动力学特征,为其剂型设计提供生物药剂学依据。
OBJECTIVE To provide biological pharmaceutical basis for dosage forms design of harmine hydrochloride by studying its absorption kinetics in various intestinal segments of rat.
用小鼠移植性肿瘤和裸鼠异体移植人肿瘤模型研究骆驼蓬总碱(TAH)抗肿瘤作用及其协同抗瘤作用。
Models of transplanted tumor in mice and human cancer xenograft in nude mice were used to evaluate the antitumor effect and synergism of total alkaloid of Peganum harmala l, (TAH).
方法采用大鼠在体肠循环法分别研究盐酸去氢骆驼蓬碱在大鼠十二指肠、空肠、回肠及结肠中的吸收动力学特征。
Method the absorption kinetics of harmine hydrochloride from duodenum, jejunum, ileum, and colon were investigated using in situ perfusion method in the rats.
目的:通过去氢骆驼蓬碱 (HM)微球与羟基喜树碱 (HCPT)注射液对大鼠正常肝细胞 (BRL )的毒性作用的比较研究 ,为HM的临床应用提供佐证。
Objective: In order to offer evidence for the clinical application of HM(harmine), toxicity of HM and HCPT(hydroxycamptothecin) against the rat normal liver cell (BRL) was compared.
目的:通过去氢骆驼蓬碱 (HM)微球与羟基喜树碱 (HCPT)注射液对大鼠正常肝细胞 (BRL )的毒性作用的比较研究 ,为HM的临床应用提供佐证。
Objective: In order to offer evidence for the clinical application of HM(harmine), toxicity of HM and HCPT(hydroxycamptothecin) against the rat normal liver cell (BRL) was compared.
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