目的:探讨药物依赖行为和酪氨酸羟化酶在成瘾过程中的相互关系。
AIM: To observe the relationship between the drug dependence behavior and levels of tyrosine hydroxylase (th) in drug acquisition process.
中文摘要:目的:建立清醒自由活动大鼠脑内酪氨酸羟化酶活性的测定方法。
Objective: To set the measuring method of tyrosine hydroxylase activity in the brain of conscious rats.
结论:NURR1基因结合神经干细胞有效改善了帕金森病模型症状,提高移植后酪氨酸羟化酶阳性神经元细胞的数量。
CONCLUSION: NURR1 gene combined with NSC can effectively ameliorate PD models symptoms and elevate the number of tyrosine hydroxylase positive neurons after transplantation.
增加EGR1表达可以激活其他信号分子的转录,包括CDK5和酪氨酸羟化酶,对神经细胞生长和分化有长期影响(2,3)。
Increased EGR1 expression activates transcription of other signaling molecules, including CDK5 and tyrosine hydroxylase, and exerts long term effects on neural cell growth and differentiation (2, 3).
方法:采用免疫组化技术和高效液相-电化学法( HPLC - EC)分别对酪氨酸羟化酶(TH)、DA进行了含量测定。
Methods: Immunohistochemistry technology and high-pressure liquid chromatography with electrochemical detector (HPLC-EC) were used to evaluated tyrosine hydroxylase (TH) and DA .
目的:探讨脑出血后抑郁动物模型脑内单胺神经递质5 -羟色胺、去甲肾上腺素、酪氨酸羟化酶的变化,研究中药颐脑解郁方对脑出血后抑郁的干预机理。
Objective: to observed the change of 5-ht, ne, th in rat brain of post hemorrhaged depression and the function of traditional medicine YINAOJIEYU to the rat of post hemorrhaged depression.
目的:探讨脑出血后抑郁动物模型脑内单胺神经递质5 -羟色胺、去甲肾上腺素、酪氨酸羟化酶的变化,研究中药颐脑解郁方对脑出血后抑郁的干预机理。
Objective: to observed the change of 5-ht, ne, th in rat brain of post hemorrhaged depression and the function of traditional medicine YINAOJIEYU to the rat of post hemorrhaged depression.
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