结论酒石酸美托洛尔片单剂量和多剂量给药后，安全性良好。
Conclusion There are good safety after administrating single and multiple oral dose of metoprolol tartrate.
前言： 目的：考察新型酒石酸美托洛尔缓释片（MT）在不同实验条件下的体外释放情况。
OBJECTIVE:To investigate the drug-release of a new metoprolol tartrate extended release tablet (MT) on different conditions.
结果表明，制得的酒石酸美托洛尔缓释片具有明显的缓释作用，体外释放符合一级释药动力学规律。
The results indicated that the sustained-release tablets had an expected sustained-release quality, and drug release pattern was in accorded with the first order kinetics.
结果表明，制得的酒石酸美托洛尔缓释片具有明显的缓释作用，体外释放符合一级释药动力学规律。
The results indicated that the sustained-release tablets had an expected sustained-release quality, and drug release pattern was in accorded with the first order kinetics.
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