目的:探讨细胞间隙通讯和细胞钙离子信号传导系统在非遗传毒性致癌物的遗传外致癌过程中的作用。
Objective: To discuss the effects of gap junction function and calcium mediated signal transduction system on nongenotoxic carcinogenesis.
大部分的遗传毒性致癌物是与DNA结合的亲电子试剂,它们直接与DNA相互作用,形成共价键,从而形成DNA -致癌物复合体,或称之为dna加合物。
Most of Genotoxic carcinogens are electrophiles that bind with DNA, and they interact directly with DNA and form covalent bond, resulting in DNA-carcinogen complexes, or DNA adducts.
大部分的遗传毒性致癌物是与DNA结合的亲电子试剂,它们直接与DNA相互作用,形成共价键,从而形成DNA -致癌物复合体,或称之为dna加合物。
Most of Genotoxic carcinogens are electrophiles that bind with DNA, and they interact directly with DNA and form covalent bond, resulting in DNA-carcinogen complexes, or DNA adducts.
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