家系中越来越早的发病和症状加重与遗传早现相一致，这在SPG3A-HSP中尚属首例。

Progressively earlier symptom onset and increasing symptom severity in this family is consistent with genetic anticipation which has not been previously reported in SPG3A-HSP.

youdao

家系中越来越早的发病和症状加重与遗传早现相一致，这在SPG3A-HSP中尚属首例。

Progressively earlier symptom onset and increasing symptom severity in this family is consistent with genetic anticipation which has not been previously reported in SPG3A-HSP.

youdao