目的介绍载药中空微球的研究进展。
Objective To review the research progress of drug-loaded hollow microspheres.
本文研究了生物降解聚合物纳米粒载药系统。
Biodegradable polymeric nanoparticles as drug delivery systems have been investigated in this dissertation.
载药海绵的抑菌效果与海绵中壳聚糖含量有关。
The effect of antibacterial of drug-loading sponges depended on the chitosan content in the sponge.
不同的处理过程对样品的载药率也有一定的影响。
Samples of different processing on drug-loading rate has a certain influence.
目的：探索用于靶向载药系统的材料与制剂方法。
OBJECTIVE: to search for a method used to make a targeting drug-carried system material and technique.
结论：载药珊瑚糊剂是一种较理想的根管充填材料。
CONCLUSION: The clindamycin loaded coral paste is an ideal as root canal filling material.
这种理解能加快制定新载药plga纳米粒的设计方案。
This level of understanding should quicken the pace of designing protocols for making new drug-PLGA nanoparticles.
目的：阐述肝靶向性壳聚糖基纳米载药体系的研究和应用。
OBJECTIVE: to introduce the research and application of liver targeting chitosan drug nano-carrier system.
结论：脂质体载药后可降低阿霉素的毒性并保留药物的抗肿瘤活性。
CONCLUSION: The liposome agent could reduce toxicities and remain its antitumor effect of adriamycin.
综述了其中载药微粒和辅料颗粒的制备方法、辅料的选择等研究概况。
The preparations of drug-loading particles and excipients particles and selection of excipients are reviewed.
该制备方法简单易行，载药率高，成本低，可实现自动化和规模化生产。
The preparation method has the advantages of simplicity, easy operation, high ratio of drug loading and low cost, and can realize automated and large-scale production.
目的采用主动载药法制备硫酸长春新碱脂质体，考察包封率的影响因素。
OBJECTIVE To prepare vincristine sulfate liposomes by active loading method, and study the influence of different factors on the entrapment efficiency.
目的探讨载药骨基质明胶(CBMG)防治人工关节感染和松动的可能性。
Objective To investigate the possibility of prevention and treatment of deep infection and aseptic loosening after joint replacement with cefazolin loaded bone matrix gelatin (c BMG).
结论正交实验结合多指标综合评价法用于载药微球的制备工艺优化实用有效。
CONCLSION Orthogonal design combined with multi-index test can be used to represent the most desirable variables in the preparation of drug-loaded microspheres.
结果联合载药情况下，不同浓度的MTX包载效果差异显著（P<0·05）。
Results The concentration of MTX showed significant influence on the co-encapsulation efficiency (P<0.05).
结论载药脂质体凝胶剂可显著促进药物经皮吸收，为经皮吸收药物的理想载体。
CONCLUSION Liposomal gel has the ability to enhance LDH transcutaneous permeation. It is effective vehicle for transdermal therapeutic drugs.
目的介绍PCL、PLGA、PLA等聚酯型高分子纳米载药系统的研究进展。
OBJECTIVE To introduce the progress of drug-loaded nano-system of polyesters such as PCL, PLGA, PLA.
载药磷酸钙骨水泥是一种集骨修复和局部药物缓释于一体的新型硬组织修复材料。
Calcium phosphate cements (CPC) are used for bone defect filling and may also be used as delivery systems for active agents.
目的探讨载药骨基质明胶(BMG)修复节段性骨缺损及防治术后感染的可能性。
Objective To explore the possibility of repair long segmental bone defects and preventing infection with cefazolin loaded bone matrix gelatin (c BMG).
载药纳米微粒是纳米技术与现代医药学结合的产物，是一种新型的药物输送载体。
The Drug loaded nanoparticle is a new technology produced by nanotechnology combined with modern medicine.
该蛋白微球新剂型改善了载药微球悬浮液的稳定性，抑制了释药初期的突释现象。
Zein microsphere tablets improved the stability of the zein microsphere enclosed drugs in suspension and suppressed the phenomenon of sudden release at the first stage of delivery.
载药纳米微粒是纳米技术与现代医药学结合的产物，是一种新型的药物输送载体。
The drug loaded nanoparticle is a new technology produced by nanotechnology combined with modern medicine. Its a new carrier of drug transport.
目的考察阳离子型壳寡糖硬脂酸嫁接物胶团的理化性质及载药胶团的体外药物释放。
Aim to prepare the micelles of stearic acid grafted chitosan oligosaccharide and investigate the drug release from micelles.
结果被动载药法制备脂质体包封率较低，主动载药制备脂质体包封率为84.38%。
ResultsThe entrapment efficiency with passive loading method was low, while up to 84.38% with active loading method.
本文主要综述了明胶、壳聚糖、聚乳酸这三种常用的可生物降解的载药微球的研究进展。
Latest research progress of microspheres containing drugs used three commonly biodegradable materials which were gelatin, chitosan and polylactide was summarized.
NLC具有的特殊结构可以提高其载药能力和制剂的稳定性，能有效的控制药物的释放。
The special structure of NLC improves its drug-loading capacity and stability, and effectively controls the release of drugs.
探讨微球制剂的载药、释药机制，为处方设计和水溶性小分子药物微球制剂的开发提供指导。
The aim of the paper is to provide helpful Suggestions for the formula design and development of microspheres loaded with small molecular and water soluble drugs.
探讨微球制剂的载药、释药机制，为处方设计和水溶性小分子药物微球制剂的开发提供指导。
The aim of the paper is to provide helpful Suggestions for the formula design and development of microspheres loaded with small molecular and water soluble drugs.
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