因此,ER介导的转录调节与DNA修复密切相关。
There is an intimate relationship between ER mediated transcription and DNA repair.
BRD7被鉴定为一个鼻咽癌密切相关新基因和潜在的核转录调节因子。
BRD7 was identified as a novel gene tightly associated to nasopharyngeal carcinoma (NPC) and also a nuclear transcriptional regulatory factor.
目前认为,信号转导和转录调节蛋白的异常是与之相关的两个可能因素。
The abnormality of signal transduction and transcriptional regulatory protein is considered as two...
结论:纹状体边缘区学习行为相关蛋白转录调节中有蛋白磷酸酶1的参与。
CONCLUSION: protein phosphatase 1 is involved in the adjustment of protein transcription related to learning behavior in the marginal division of striatum.
以反转录调节基因转殖,转换具有ADA基因的自体造血干细胞对他们进行治疗。
They were treated with transduced autologous hematopoietic stem cells transfected with the ADA gene, inserted via retroviral-mediated transfer.
本研究对拟南芥一个可能的转录调节因子ceo2功能及其介导重金属伤害的分子机制进行了分析。
This research analysed the function of CEO2, a potential transcription regulator factor, and the molecular mechanism of heavy metal injury.
已有研究表明DNA顺式作用元件与反式作用因子之间的相互作用是染色质重塑和基因转录调节的基础。
Present studies indicate that the interactions between trans-acting factors and corresponding DNA cis-acting elements are the basis of chromatin remodeling and gene transcription regulation.
转录因子ap - 2就在许多参与哺乳动物发育、分化和癌症形成的基因转录调节中起到了重要的作用。
Transcription factor AP-2 plays an important role in regulating transcription of a number of genes in mammalian development, differentiation and carcinogenesis.
而那些低表达的基因,功能涉及转录调节、小泡运输、铁代谢、信号转导,以及细胞外基质的组成和生物转化。
The genes with lower expression function in areas such as transcription regulation, vesicular transport, iron metabolism, signal transduction, and extracellular matrix organization and biogenesis.
HAP1基因编码的一个复杂的转录调节许多基因参与了电子转移反应,是必不可少的厌氧或血红素枯竭条件。
The HAP1 gene encodes a complex transcriptional regulator of many genes involved in electron-transfer reactions and is essential in anaerobic or heme-depleted conditions.
前期对模式植物拟南芥的研究,鉴定出几个转录调节因子通过调节裂区不同细胞形态的分化形成参与了拟南芥角果的开裂过程。
Recent studies on Arabidopsis have identified several transcriptional factors involved in fruit dehiscence by regulating the proper differentiation of cell types in dehiscence zone.
以含雌激素反应元件的荧光素酶(ERE -LUC)为报告基因,通过检测荧光素酶活性来确定MDM2是否对ER有转录调节因子的作用。
The effect of MDM2 on the transcriptional activity of er was detected by the reporter gene containing estrogen responsive elements luciferase (ERE-LUC).
例如,电路可以模拟出乳糖代谢基因与调节细菌细胞内乳糖代谢基因表达的转录因子之间的互动过程。
For example, circuits can simulate the interactions between genes involved in lactose metabolism and the transcription factors that regulate their expression in bacterial cells.
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子,它可以EGR响应元素(ER),调节靶基因的表达(1)。
EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
为了了解LXR如何调节低密度脂蛋白受体,作者研究了LXR靶基因的转录,并确定了一个能编码肌球蛋白互动蛋白的基因,IDOL。
To understand how LXR regulates LDLR, the authors examined transcriptional target genes of LXR and identified a gene that encodes a myosin interacting protein, IDOL.
自然界中有一类名为转录因子的蛋白可调节(升高或者降低)基因的活性,该技术正是基于该机理。
The technique relies on a natural process by which the activity of genes is raised or lowered by proteins called transcription factors.
在真核生物中基因表达的调节主要是在转录水平。
Gene expression in eukaryotes is regulated primarily at the level of transcription.
这些结果说明opbp1基因可能作为一转录因子来调节烟草耐盐相关的基因。
These results suggested that OPBP1, as a transcription factor is involved in the regulation of salt stress related genes.
我们也对不同水平下调节自噬的分子机制(从转录激活作用到翻译后蛋白修饰作用)方面的最新进展做了文献复习。
We also review the recent advances on the molecular mechanisms that regulate the autophagy machinery at various levels, from transcriptional activation to post-translational protein modification.
转录后调节控制流程的速度和蛋白质的生产时间和最最重要的是适当的细胞功能。
Posttranscriptional control processes regulate the rate and timing of protein production and are of central importance to proper cellular function.
这一作用主要通过活化蛋白激酶C(PKC)通路来实现,而CD133抗原表达可能是转录后进行调节。
This function is accomplished through activating the PKC, and the expression of CD133 is regulated possibly after transcription.
热激转录因子在调节植物对逆境胁迫应答和热激蛋白基因表达方面起重要作用。
Heat shock transcription factors (HSFs) are important in regulating heat stress response by mediating expression of heat shock protein (HSP) genes in various plant species.
PPAR的主要功能是调节基因的转录。
The main function of PPAR is to regulate the transcription of genes.
SITR 1是一种组蛋白脱乙酰基酶,一种能够阻断来自调节基因的转录因子的蛋白质。
SITR1 is a histone deacetylase, a protein that blocks transcription factors from regulating genes.
生物钟相关基因相继被分离鉴定,它们及其编码的蛋白质产物构成的自主调节的转录和翻译反馈环是生物钟运转的分子机制。
The clock genes and the coded protein comprise the self-sustaining feedback loop that can regulate both on the transcriptional and on the translational level.
本文主要就组蛋白乙酰转移酶调节基因转录以及组蛋白去乙酰化酶抑制剂促进记忆形成的作用机理进行综述。
In this paper, we reviewed the mechanisms on histone acetyltransferases regulating gene transcription and histone deacetylase inhibitors promoting memory formation.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上,从而在转录水平上调节基因的表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
常规的思维认为如果不是基因机构不同,那一定是基因转录蛋白的调节方式不同。
Conventional wisdom has been that if the difference is not the gene content, the difference must be in the way regulation of genes produces their protein products.
LPL活性调节的这种组织特异性主要是由于不同组织lpl基因转录速率不同所决定的。
The tissue-specific changes in LPL activity can be determined by the different rate of LPL gene transcription in different tissue.
LPL活性调节的这种组织特异性主要是由于不同组织lpl基因转录速率不同所决定的。
The tissue-specific changes in LPL activity can be determined by the different rate of LPL gene transcription in different tissue.
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