目的:探讨高原低压缺氧暴露过程中大鼠心肌能量代谢及腺苷酸转位酶活性变化特点。
AIM: To explore the changes of myocardial energy metabolism and adenine nucleotide translocase (ANT) activity in mitochondria in rats exposed to hypoxia.
现已发现,氧化应激可以改变端粒酶活性,促使端粒酶从细胞核转位到线粒体,因而不能继续维持端粒长度,使细胞端粒缩短。
It has been demonstrated that telomerase activity would be altered upon oxidative stress and excepted from nucleolus to mitochondria as well as telomere shortening.
现已发现,氧化应激可以改变端粒酶活性,促使端粒酶从细胞核转位到线粒体,因而不能继续维持端粒长度,使细胞端粒缩短。
It has been demonstrated that telomerase activity would be altered upon oxidative stress and excepted from nucleolus to mitochondria as well as telomere shortening.
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