一种方式是,研发出能紧密结合免疫细胞上受体的药物,以便诱导产生IL - 10。
One approach could be to develop drugs that can bind tightly to the receptors on immune cells and induce the production of the anti-inflammatory IL-10.
药物的精确结合能够激发或抑制特定受体的正常活性,从而在产生更有力的治疗的同时使副作用最小化。
Precise binding by a drug can stimulate or block that particular receptor's normal activity, leading to more powerful treatment while minimizing bothersome side effects.
几乎没有什么心脏药物只结合一个受体。
Very few drugs that act on the heart bind to just one receptor.
第二个稍大剂量药物注射后,因为“备用受体”已经被结合,所以药物的起效时间可以缩短。
The second, much larger dose is then administered and the speed of onset decreased secondary to the "spare" receptors already being bound.
现代药理研究表明:药物发挥作用的首要步骤是与细胞膜上的某些受体或通道结合。
Modern pharmacological studies have shown that combination with some receptors or channels on cell membrane is the first step of drug action.
玻璃体结合蛋白受体的新的拮抗剂衍生物,它们的制备方法,它们作为药物的应用和包含它们的药物组合物。
Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same.
如何在生物胺受体结构数据严重匮乏的基础上研究受体的配基结合位点及其它功能位点,已成为药物设计中的关键问题。
The principal question in drug design is how to study the ligand-binding sites and others because of the poor structure information.
方法:结合国外文献简述组胺h 4受体配体作用机制的研究进展以及药物治疗的前景。
Methods By combining the foreign literatures, the progress in the mechanism research of histamine H4 receptor ligands and the prospect of drug therapy with H4 receptor ligands are introduced.
目的观察补中益气汤等药物血清对离体脾虚大鼠胃壁细胞胃泌素受体结合容量的影响。
To observe the effects of the serum with the BZYQD on the binding of gastrin with its receptors on parietal cells of spleen-deficiency rats in vitro.
本发明还公开了含有所述化合物的药物组合物和药物联用以及它们用作凝血酶受体拮抗剂和类大麻醇受体结合剂的用途。
Also disclosed are pharmaceutical compositions and combinations containing said compounds and their USES as thrombin receptor antagonists and binders to cannabinoid receptors.
本发明还公开了含有所述化合物的药物组合物和药物联用以及它们用作凝血酶受体拮抗剂和类大麻醇受体结合剂的用途。
Also disclosed are pharmaceutical compositions and combinations containing said compounds and their USES as thrombin receptor antagonists and binders to cannabinoid receptors.
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