它是一种自身抗原，其天然抗体不与体细胞LDH同工酶发生交叉反应。
Antibody against native LDH-C4 is specific to spermtozoa and is not cross-reactive with somatic LDH isozymes.
但这些抗原多属自身抗原，普遍存在免疫原性低，易引起免疫耐受等缺陷。
But most of the antigen was the kind of self-antigen with the defects of poor-immunogenicity and easily-caused immunotolerance.
研究发现，来源于胶原蛋白以及非关节源性蛋白的自身抗原可引起特异性的T细胞反应。
Recently, self-antigens derived from collagen and non- arthritogenic proteins were demonstrated to bind to HLA-B27 molecule and cause specific T cell responses.
眼眶自身抗原的表达诱发机体免疫平衡状态紊乱，免疫功能活化，进而对眶内组织产生免疫损害。
Orbital tissue lesion is due to the activation of autoimmune state stimulated by the expression of autoantigen in orbit.
乳糜泻的病人是由于对谷蛋白的反应而引起小肠炎症，然而目前还没有明确的自身抗原导致克罗恩病。
Celiac patients develop an inflammation of the small bowel in reaction to gluten, whereas there is no specific known autoantigen for Crohn's disease.
二者的平衡使机体在避免对自身抗原产生不适当反应的同时，又能对外来抗原显示足够强的应答能力。
The balance between two kinds of signals ensures an effective response to foreign antigens for host protection, while avoiding inappropriate reaction to self antigens.
小剂量口服自身抗原诱导免疫耐受可有效地抑制EAE和MS，这已被诸多研究所证实，但其机制尚不清楚。
Oral tolerance by feeding autoantigens is an effective method to prevent EAE and to treat MS, which mechanism has not been made very clear.
未成熟T细胞通过TCR-CD3 复合物与自身抗原接合激活上述过程可能与克隆清除的形成机制及自我耐受有关。
Activation of this process in immature T cell by the bindng of the TCR CD3 to self antigens may therefor be the mechanism which produces clonal deletion and consequently self tolerance.
这项新的研究显示，哪怕是只有一种自身抗原没有被识别为“自身”成分，这个识别缺欠就有可能会导致视网膜发生严重的自身免疫性疾病。
The new research showed that if just one of the body's antigens is not recognized as "self," this single failure can lead to a severe autoimmune disease in the retina.
他接着说，“有人提出‘如果我们能够知道是某个自身抗原引起的疾病，我们就能针对个别的机体蛋白质或抗原进行治疗’的假说，这个研究发现支持这种假说。”
"The finding supports the promise of treatments targeting individual body proteins or antigens since we have shown that a single self-antigen can trigger disease, " he added.
这些我们成为抗原的分子被一些称作受体细胞所吸收，并将它们吸附在自身表面暴露给助细胞。
These molecules, known as antigens, are picked up by so-called antigen-presenting cells that display them on their surfaces and show them to the helper cells.
当具有攻击性的，引起自身免疫疾病的T细胞从死的β细胞处得到抗原，他们会持续攻击β细胞。
When the aggressive, autoimmune disease-causing T cells are presented with antigens from dying beta cells, they keep attacking and killing the beta cells.
是由于生殖系统抗原的自身免疫或同种免疫引起。
Is because reproductive system antigen's own immunity or the homogeneous immunity cause.
而对于那些自身免疫紊乱的病人来说，他们的免疫系统无法分辨正常的组织与抗原。
In patients with an autoimmune disorder, the immune system can't tell the difference between healthy body tissue and antigens.
这些数据提示，疾病共同的生物学机制，比如有关自身免疫的组织损伤和对食物中抗原的不耐受，可能这两种疾病的共同病因。
These data suggest that common biologic mechanisms, such as autoimmunity-related tissue damage and intolerance to dietary antigens, may be etiologic features of both diseases.
目的定量检测各种结缔组织疾病（CTD）患者血清中抗可提取核抗原（ENA）自身抗体滴度，并探索其临床意义。
Objective To study the clinical significance of the quantitative determination of the various anti extracted nuclear antigens(ENA) autoantibodies in the various connective tissue disease (CTD).
结论白癜风患者血清中存在抗mchr1的自身抗体，MCHR1是MC膜表面的白癜风相关抗原。
Conclusion There are anti-MCHR1 antibodies in sera of some patients with vitiligo. MCHR1 is one of vitiligo related antigen and it is located on melanocyte membrane.
抗原提呈组与自身对照组相比，各指标无统计学差异。
There was no significant difference between own control group and antigen presentation group.
免疫系统会攻击外来的不相匹配的抗原，例如说接受移植的患者自身免疫系统会排斥捐赠的器官。
The immune system will attack foreign antigens. For example, without closely matched antigens, a transplant patient's immune system will reject a donated organ.
目的克隆白癜风患者淋巴细胞中原始配对的自身抗体基因，构建噬菌体抗体库并筛选针对黑素细胞膜抗原的特异性抗体。
AIM: To obtain in situ pairing of the variable region genes of the heavy and light chains of vitiligo patients' lymphocytes, then construct and screen a human ScFv phage antibody library.
RA的发病机制不清，近几十年的研究已证实感染和受抗原驱动的自身免疫反应是RA发病和病情迁延的中心环节。
Extensive researches over the last few decades have provided data to support the hypotheses that RA is an antigen-driven, autoimmune disease.
作为一种自身免疫性疾病，类风湿性关节炎的发病与异常的抗原抗体反应息息相关。
As an autoimmune disease, rheumatoid arthritis, and the incidence of abnormal antigen-antibody reactions are closely related.
大疱性类天疱疮是一种慢性病，其自身抗体可以同两种半桥粒抗原反应，大疱性类天疱疮抗原180和大疱性类天疱疮抗原。
Autoantibodies in bullous pemphigoid, which is typically a chronic disease, react with 2 hemidesmosomal antigens, bullous pemphigoid180 and bullous pemphigoid.
近年来通过口服抗原(耐受原)诱导免疫耐受，靶向性治疗自身免疫病的研究日益受到关注。
The therapy of autoimmune diseases by inducing oral immune tolerance has progressed a lot recently.
结果：该方法纯化所得的自身抗体，能特异性地结合其所针对的靶抗原。
Results:The BMZ-Ab purified by this method could specific ally combine its target-antigen.
上述观察结果为阐明自体抗原的半抗原化为何会引起自身免疫性疾病提供了一种似乎合理的解释。
The observed results provide a plausible mechanism for how haptenization of self-antigens can lead to the development of autoimmunity.
上述观察结果为阐明自体抗原的半抗原化为何会引起自身免疫性疾病提供了一种似乎合理的解释。
The observed results provide a plausible mechanism for how haptenization of self-antigens can lead to the development of autoimmunity.
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