然后再与A环合成子偶联、关环、脱保护完成目标产物的全合成。
Then coupling with A ring synthon, closing, deprotection, the aim product was synthesized finally.
所以下面给出的例子既有脱保护的步骤a,又有伴随成盐的步骤b。
Therefore, those examples given below that show the de-protection step (a) also show the concomitant salt formation step (b).
方法:以芦丁为原料,经苯甲酰化,水解,糖苷缩合和脱保护合成目标化合物。
Methods: Rutin was utilized as the starting material. The target compounds were produced via benzoylation, hydrolysis, glycosidation and deproteination.
红霉素碱经肟化、保护再经甲基化、脱保护得到克拉霉素,总收率达40 %以上。
Clarithromycin was prepared from erythromycin a through oximation, protection, methylation and deprotection. The overall yield of clarithromycin was 40%.
方法以固相亚磷酰胺法合成吖啶、6碳氨基连接臂修饰的TFO ,并以温和法切割和脱保护;
Method TFO modified by acridine and amino modifier C6 were synthesized by solid phase phosphoramidite chemistry, then deprotected mildly.
以D-(-)-果糖为手性源,经过丙酮保护、氧化、选择性脱保护、三氟酰化四步反应得到手性酮4。
Chiral ketone 4 derived from D-(-)-fructose was obtained by four steps reaction including protection with acetone, oxidation, deprotection selectively and trifluroacetylation.
方法采用对硝基苯胺为原料,经还原、加保护基、甲酰化、氯化、环合、脱保护基六步反应法可进行化学合成。
Methods Apraclonidine was synthesized from P-Nitraniline by reaction with reduction, adding protection group, formylation, chlorination, cyclization, off-protecting group.
方法:以廉价易得的谷氨酸和丙氨酸为起始原料,经端基保护、脱保护、缩合等步骤得到一个有效的合成路线。
Methods: An efficient route was started from the cheaper materials alanine and glutamic acid via protection, deprotection and coupling reactions.
目前,合成过程的中间监测方法主要集中在胺酰化及脱保护反应,而对于中间体一活化酯的反应进程没有监测方法。
Currently, the reaction progress monitoring focuses on amide acylation and deprotection reaction, while there is no method for the reaction progress of the intermediate-active esters.
在最后一步脱保护基的研究中,我们分别采用了锌粉还原和钯碳氢化两种方法得到最终产品,并对其后处理的方法进行了改进。
In the last step, we developed two methods of deprotection employing zinc dust and catalytic hydrogenolysis respectively to give the final product, and improved the work-up as well.
但是,这两国在监测和保护大象免遭杀戮方面的记录欠佳,并与过去10年爆发的大规模偷猎活动有脱不掉的干系。
But both places have poor records of monitoring and policing their elephant populations, and have been heavily implicated in epidemics of poaching that have broken out in the last decade.
我不求你将他们从世界上撤去,只求你保护他们脱免邪恶。
I do not ask you to remove them from the world but to keep them from the evil one.
是求天主免我们灵魂肉身的患难,格外保护我们不犯罪,脱免地狱的永苦。
This is the prayer that God may save us from all calamities of soul and body, especially from committing sin and from the everlasting pains of Hell.
用二氯亚砜将萘普生酰氯化,在氮气保护下与脱镁叶绿酸交联,以硅胶柱层析分离产物。
Naproxin was treated by thionyl chloride, then conjugated to Phaeophorbide under protection of N2. The compound was purified by silica gel column.
以蔗糖为起始原料,经羟基选择性保护、氯化、脱乙酰基等3步化学反应合成三氯蔗糖;
Sugar was as the start material by the reaction of the selective protections at 6-hydroxy, chlorination, deacetyl in three steps obtained the target compound(trichlorosucrose);
介绍了FZC系列渣油加氢保护剂和脱金属催化剂的研制、生产和工业应用。
Development, production, and commercial application of the FZC serial residue hydrotreating guard assistant and demetallization catalyst were introduced.
目的:观察和比较两种浓度氟保护漆在体外抑制人牙釉质脱矿的能力。
Objective:To observe and compare the inhibitory effect of two concentrations of fluor protectors on demineralization of human enamel in vitro.
目的观察臂丛根性撕脱伤后神经干细胞脊髓内移植对前角运动神经元的保护作用。
Objective to investigate the protective effect of transplantation of neural stem cells into spinal cord on the survival of motoneurons after brachial plexus root avulsion injury.
摩脱车手辟须带头盔保护卦蓟免受伤害。
活泉补水配方,舒缓干燥、红痒和脱屑等敏感症状,提高肌肤自我保护功能,肌肤散发健康光泽。
Combine active spring aqua formula, it can relieve dry, reddish, itching, peeling and sensitive skin, strengthen the self-protection function of skin, and make skin healthy and bright.
目的本实验评估体外脱矿环境中氟保护漆对覆盖义齿基牙的防龋作用,为临床预防覆盖义齿基牙龋坏提供参考。
Objective:To study and evaluate the effect preventing dentine hypersensitivity by using GlumaTM or Fluor Protector on the prepared vital pulp abutment teeth of the crown.
高结晶温度的保护渣具有较强的脱玻化能力,且脱玻化温度较低;
The powder for higher crystallization temperature has stronger crystallization capability in annealing and lower devitrified temperature;
高结晶温度的保护渣具有较强的脱玻化能力,且脱玻化温度较低;
The powder for higher crystallization temperature has stronger crystallization capability in annealing and lower devitrified temperature;
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