事实上，当嘌呤存在于肽核酸的链上时，肽核酸-DNA二聚体的稳定性会大大增加。
In fact PNA - DNA duplexes show significantly increased stability when the purines are in the PNA strand.
结论利用肽核酸生物传感器成功地绕过了PCR扩增而直接检测出了临床标本中的HBV基因组dna。
CONCLUSIONS HBV DNA extracted from clinical samples were directly detected using PNA biosensor and PCR amplification was successfully bypassed.
因此，肽核酸- DNA二聚体的稳定性除了依赖g - C配对的含量外，还与肽核酸链上的嘌呤含量有关。
Thus on top of the dependence on g-c content, the stability of pna-dna duplexes also depends on the purine fraction of the PNA strand.
肽核酸(PNA)作为一种反义核酸类化合物，在分子水平的疾病诊治上，有其独特的优越性，现在日益受到关注。
PNA, which is one kind of anti sense nucleic acid compounds, has its unique advantages in the molecular diagnostics and treatment of diseases. Now, people gradually attach more importance to PNA.
此外，鉴于肽核酸独特的理化和生物学性能，人们正尝试将其用于生物分子工具、反义和反基因制剂、分子探针和生物传感器。
In addition, the unique chemical, physical and biological properties of PNAs have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.
此外，鉴于肽核酸独特的理化和生物学性能，人们正尝试将其用于生物分子工具、反义和反基因制剂、分子探针和生物传感器。
In addition, the unique chemical, physical and biological properties of PNAs have been exploited to produce powerful biomolecular tools, antisense and antigene agents, molecular probes and biosensors.
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