目的：寻找抑制肺动脉高压肺血管重建的药物。
Objective: to find a therapeutic inhibitor of vascular remodelling in pulmonary hypertension.
结论低氧所致CTGF的合成增多在低氧性肺血管重建和肺动脉高压的发病过程中起一定的作用。
Conclusions: the CTGF may play an important role in the pathogenesis process of hypoxic pulmonary vascular remodeling and pulmonary hypertension.
结果：低氧2周后出现大鼠肺血管结构重建。
Results: Pulmonary vascular structural remodeling developed after 2 week hypoxia.
目的探讨一氧化碳对缺氧性肺血管结构重建大鼠肺动脉中转移生长因子(TGF)表达的影响。
Objective to investigate the impact of transforming growth factor (TGF) in the mechanisms by which carbon monoxide (CO) regulates hypoxic pulmonary vascular remodeling.
肺血管平滑肌细胞是肺血管收缩反应的主要执行者，也是肺血管结构重建的重要参与者。
Pulmonary vascular smooth muscle cell is an important executor of vasoconstriction and a key contributor of pulmonary vascular structure remodeling.
结论肺切除合并受肺癌侵犯的心脏大血管切除重建术能明显提高患者的生存率，改善患者预后。
Conclusion Extended resection of the heart, great vessels or both can remarkably increase the long term survival and improve the prognosis in patients with locally advanced lung cancer.
结论：肺心合剂能部分逆转肺血管结构重建，有效降低肺动脉高压。
CONCLUSION: Feixin mixture reverses partially the remodeling of pulmonary vascular structure and reduces effectively pulmonary hypertension.
结论一氧化碳对缺氧性肺血管结构重建大鼠肺动脉中TGF表达有抑制作用。
Conclusion Carbon monoxide inhibited TGF expression by pulmonary arteries of rats with hypoxic pulmonary vascular remodeling.
结论一氧化氮对缺氧性肺血管结构重建大鼠肺动脉中PDGF表达有抑制作用。
Conclusion Nitric oxide inhibited PDGF expression by pulmonary arteries of rats with hypoxic pulmonary vascular remodeling.
结论一氧化氮对缺氧性肺血管结构重建大鼠肺动脉中PDGF表达有抑制作用。
Conclusion Nitric oxide inhibited PDGF expression by pulmonary arteries of rats with hypoxic pulmonary vascular remodeling.
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