原发性骨肿瘤中检出GNAS突变有利于临床诊断纤维性结构不良。
The detection of GNAS mutations in primary bone tumors has been useful in clinical practice for diagnosing fibrous dysplasia.
因此我们的研究与先前的研究一致，GNAS的突变在纤维性结构不良中有高度特异性，而在骨旁骨肉瘤和其它低级别骨肉瘤中即使有GNAS突变、也是很少的。
Our findings therefore support prior observations that GNAS mutations are highly specific for fibrous dysplasia and occur rarely, if ever, in parosteal and other low-grade osteosarcomas.
目的：比较分析肢体单灶性纤维结构不良的手术治疗方法。
Objective: to analyse and study the surgical treatment of monostotic fibrous dysplasia of extremities.
方法用HE及SP法免疫组织化学染色对5 2例形态学变异的纤维结构不良作回顾性分析。
Methods HE staining and immunohistochemical staining technology (S-P method) were used to do retrospective analysis for 52 cases of fibrous dysplasia, which had morphologic abnormalities.
方法用HE及SP法免疫组织化学染色对5 2例形态学变异的纤维结构不良作回顾性分析。
Methods HE staining and immunohistochemical staining technology (S-P method) were used to do retrospective analysis for 52 cases of fibrous dysplasia, which had morphologic abnormalities.
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