目的:研究某些中药有效成分对非酶糖基化的抑制作用。
Objective: to investigate the inhibitory effects of some Chinese herb components on the nonenzymatic glycosylation.
已糖胺的生物合成是蛋白质和脂质糖基化的基本途径(2)。
The hexosamine biosynthesis pathway generates the building blocks for protein and lipid glycosylation (2).
炎症反应过程是选择素家族成员与其糖基化的配体相互作用的结果。
The inflammation reaction depends on the function of the members of selectin family and their glycosylated ligand.
目的研究牛磺酸对糖尿病大鼠肾脏氧化应激反应和非酶糖基化的抑制效果。
Objective to investigate the inhibitory effects of taurine on oxidative stress and nonenzymatic glycation in kidney of diabetic rats.
这种糖基化的胶原可以作为糖尿病和老龄化等因素造成的ECM改变的体外模型。
These gels could be used as in vitro models to study ECM changes that occur in diabetes and aging.
硫酸乙酰肝素并不是一种蛋白质,在某种程度上它只是经常参于糖基化的一种富硫的、类糖的分子。
Heparan sulphate is not a protein. It is, rather, a sulphur-rich sugar-like molecule of a sort often involved in glycosylation.
许多病毒抗原都有糖基化的现象,糖基化会改变病毒对宿主的免疫逃避、病毒抗原的免疫原性等。
Many viral antigens are glycosylated, different glycosylation will influence the immunogenicity and immune evasion of virus.
糖基化的出现使细胞的多糖经常连接到蛋白和脂质的过程成为一个丰富多样并且高度受调控的过程。
Glycosylation produces an abundant, diverse, and highly regulated repertoire of cellular glycans that are frequently attached to proteins and lipids.
目的研究糖基化终末产物对正常大鼠肾脏功能和结构的有害作用及拟黑多刺蚁醇提物对糖基化的抑制作用。
Objective To study the deleterious effect of glycation end products on normal rat renal structure and function and inhibiting effect of Polyrhachis vicina roger extraction on glycation.
去糖基化的小麦PGIP不能与纯化的天然PGIP产生的抗体发生免疫学反应,可能是由于小麦PGIP中寡糖链为抗原决定部位。
After deglycosylated, wheat PGTP could not interact with antibody produced by purified native PGtP from wheat. It is the glycans of wheat PGIP that probably fonn the epitope.
这些数据表明晶状体蛋白的非酶糖基化可能会导致白内障。
These data suggest that nonenzymatic glycosylation of lens crystallins may contribute to cataract formation.
去糖基化后,小麦PGTP与天然纯化的 PGTP产生的抗体不发生相互作用。
After deglycosylated, wheat PGTP could not interact with antibody produced by purified native PGtP from wheat.
硫酸乙酰肝素是肝磷脂的前体,是重要的抗凝剂,目前只能从血液中提取,从未成功合成提取过,它并不是蛋白质,而是一种富硫似糖的分子,经常参与糖基化反应。
This is a precursor to heparin, an important anti-clotting agent that has, at present, to be extracted from blood, rather than being synthesised. Heparan sulphate is not a protein.
结果表明,与生理盐水对照组相比,青蒿素及其糖基化衍生物均可有效抑制肿瘤的生长和延长小鼠寿命,毒性实验表明属于低毒类物质。
Compared with normal sodium, the results showed artemisinin and its glycosylated derivates can suppress growth of tumor and increase in life span of mouse.
过多的糖基化似乎对器官损害,在糖尿病发生的原因之一。
Excessive glycosylation appears to be one of the causes of the organ damage that occurs in diabetes.
蛋白质糖基化在细胞的功能行为中起重要的作用。
Glycosylation of protein plays important roles in the function of cells.
目的:分离两种极性极为相似的寡糖异构体并对一种新的糖基化方法进行初步探索。
Objective: To separate two oligosaccharide isomers which have very similar polarity and to try a new method of glycosylation.
糖基化反应可以改善蛋白质的某些功能特性。
Functional properties of proteins can be improved by mallard reaction.
当血糖过多时,可以使上述酶的酶蛋白糖基化,催化活性降低,过暇化氢和氧自由基清除减慢。
When hyperglycaemia, may cause the above enzyme the zymoprotein glycosylation, the catalytic activity to reduce, crosses the free time hydrogen and the oxygen free radical elimination reduces speed.
糖基化是通过改变蛋白质表面电荷和形成双亲结构来改善乳化性的。
Emulsify properties were improved by glycosylation through change of surface charge and formation of amphiphilic structure.
糖基化是机体蛋白质翻译后的一种重要的修饰过程。
N-glycosylation of proteins is an important post-translation modifying process in organism.
研究了白花曼陀罗细胞悬浮培养对外源氢醌的糖基化。
To investigate the biotransformation of hydroquinone by cell suspension cultures of Datura stramonium.
目的以非酶糖基化和自由基学说探讨心肌老化的发生机制。
Objective To investigate the mechanisms of nonenzymatic glycosylation inducing myocardial aging and free radical theory.
目的为探讨糖基化产物对正常肾脏的特异性损害作用。
Objective To explore the specific pathogenic role of glycation products in normal kidney.
结论阿斯匹林和布洛芬可部分保护糖基化诱导CAT和SOD的失活。
CONCLUSION Aspirin and ibuprofen show partial protection against the glycation induced inactivation of SOD and cat.
蛋白质的糖基化是最重要的翻译后修饰之一,与蛋白质结构和功能的关系密切。
As one of the most important post-translational modifications, glycosylation has a significant effect on the structure and functions of proteins.
糖基化反应是改善蛋白质功能特性的一种有效的方法。
Glycosylation is an effective method of improving functional property of protein.
糖基化反应是改善蛋白质功能特性的一种有效的方法。
Glycosylation is an effective method of improving functional property of protein.
应用推荐