神经管畸形；病例对照研究；危险因素。
叶酸能帮助防止诸如脊柱裂等神经管畸形出生缺陷的发生。
Folic acid helps prevent neural tube birth defects such as spina bifida.
神经管畸形发生率增加，唇腭裂、肢体畸形减少。
目的：探讨牡蛎提取物对高温致神经管畸形中凋亡细胞的保护作用。
Objective: to explore the protective effect of oyster extract on apoptotic cells in neural tube defect (NTD) induced by hyperthermia.
发生率最高的神经管畸形是脊柱裂，其他依次为无脑畸形、脑膨出、小头畸形。
The highest of neural tube defects is spina bifid a then is anencephaly encephalocele and so on.
目的探讨北方乡村妇女亚甲基四氢叶酸还原酶（MTHFR）基因多态性与神经管畸形的关系。
Objective To explore relationship between methylenetetra hydrofolate reductase (MTHFR) polymorphism and neural tube defects (NTDs)of women in the northern countryside.
结果在17例畸形胎儿中，单发性14例，多发性3例，神经管畸形发生率最高（6/17）。
Results In the 17 case of abnormal fetus, 14 cases were simple and 3 cases were complicated, nerve system anomaly occur rate is hightest(6/17) .
结论被动吸烟可以促使神经管上皮细胞的过度凋亡，可能是导致神经管畸形发生的重要原因之一。
Conclusion Passive smoking can cause excessive apoptosis in neural epithelium, which may be one of the important ways by which the deformation of neural tube will occur.
唐氏综合征患者的血清甲胎蛋白升高20- 25%，胎儿有神经管畸形时甲胎蛋白值也升高。
Maternal serum alpha-fetoprotein is elevated in 20-25% of all cases of Down syndrome, and it is elevated in fetal neural tube deficits.
本文旨在研究定位转新基因(HCY -2)与神经管畸形发生的时间-效应关系及可能的作用机理。
The time effect relationship between positional transfered novel gene (HCY 2) and neural tube teratogenesis, and their possible mechanisms were studied.
了解育龄妇女对神经管畸形的认知程度和对增补叶酸预防神经管畸形的积极性，评估神经管畸形知识的宣传效果；
To assess the awareness of NTDs among the reproductive-aged women and their initiative and compliancy about using folic acid to prevent the NTDs.
结论：我省1997到2004年出生缺陷监测出生缺陷总发生率和神经管畸形发生率均呈逐年下降趋势，且下降幅度基本一致。
Conclusion: From 1997 to 2004, the comprehensive occurrence possibility and Nerve Tube Defects (NTDs) occurrence possibility appear a decrease trend year by year, moreover, the scope keep the same.
最常见的神经管缺陷是脊柱裂，它是指胎儿期脊髓没有被完全封闭，和无脑畸形，它指部分或全部脑组织没有发育。
The most common neural tube defects are spina bifida, in which the spin al cord fails to close completely during fetal development, and anencephaly, in which part or all of the brain doesn't develop.
出生缺陷前五位的是唇腭裂、神经管发育畸形、无脑儿、先天性心脏病、脐疝；
The top five birth defects are cleft lip and palate, neural tube development defects, no brain child, congenital heart disease, umbilical hernia;
出生缺陷前五位的是唇腭裂、神经管发育畸形、无脑儿、先天性心脏病、脐疝；
The top five birth defects are cleft lip and palate, neural tube development defects, no brain child, congenital heart disease, umbilical hernia;
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