这种专一性可能寄寓在分子的碱基对顺序之中。
This specificity probably resided in the sequence of base pairs along the molecules.
其双链链长,经凝胶电泳分析,约为500碱基对。
The lengths of the double stranded cDNA fragments were about 500 base pairs.
人类基因本身就有接近 30 亿个DNA碱基对。
The human genome alone has approximately 3 billion DNA base pairs.
尿嘧啶--核糖核酸中的一种嘧啶,与腺嘌呤形成碱基对。
Uracil -- a pyrimidine found in RNA that base-pares with adenine.
全基因共由246个碱基对组成,编码一个75肽的复合抗原。
The gene was composed of 246 base pairs and coded for a hybrid antigen of 75 amino acids.
通过转动电场的极性,DNA链会渐进式地前进,一次一对碱基对。
By flipping this field's polarity the DNA strand can be ratcheted along, one base pair at a time.
而且现有的测序技术要把DNA破碎成少于100个碱基对的小片段。
Moreover, existing sequencing techniques involve breaking DNA into small chunks of less than 100 base pairs.
这时需要引入计算机,对个人基因组序列中的30亿组碱基对进行比较。
This is where the computing comes in. Computers allow individual genomes-all 3 billion base pairs of them-to be compared.
仅仅一条DNA链就可以被识读出来,一次一个碱基对,不需要带上标识。
Instead a single strand of DNA can be read, one base pair at a time, and without the need for labelling.
不过,在这些实验中,碱基对通过开口时移动太快,难以准确的读取代码。
But in those experiments, the base pairs moved too quickly through the openings for the code to be read accurately.
研究人员发现,鸭嘴兽有大约22亿个碱基对,是人类碱基对数量的三分之二。
At roughly 2.2 billion base pairs, the platypus genome is about two-thirds the size of the human genome, the researchers found.
考虑到碱基对梯阶间的非紧邻相互作用,提出DNA宏观弯曲的经验预测规则。
Empirical rules, which take into account the non-neighbor interactions between the base-pair steps, have been presented to predict DNA curvature.
给出DNA宏观弯曲的定义,使用联系碱基对梯阶间的变换矩阵计算宏观弯曲。
A definition of DNA curvature has been made. The transformation matrix involving the angular parameters relating successive base-pair steps has been used to investigate the DNA curvature.
碱基对一个接一个地平放在平行的平面上,产生一种它们是‘堆放’在那里的印象。
Base pairs lie in parallel planes one above the other, giving the impression that they are 'stacked.
所用的菌种为TA98和TA10 0 ,主要考察碱基对置换突变和移码致突变。
In Ames assay the strains were TA98 and TA100, which were able to determine base pair substitutions and frameshift mutation respectively.
“我们有大约1019个碱基对需要分析,而我们甚至都没来得及弄懂一些皮毛,”他说。
“We’ve got about 1019 base pairs to read before we’ve even scratched the surface, ” he says.
所有位点都包含称为短串联重复序列的遗传结点,在结点里一个碱基对模式一遍遍重复出现。
All of these regions contain genetic stutters called short tandem repeats, in which a pattern of base pairs repeats itself over and over.
研究人员也主张,仅仅根据一个DNA碱基对的遗传变异,就可以评估不同种族的健康风险。
Researchers have also advocated assessing health risks within ethnic groups based on inherited variations in just one DNA base pair.
因此内共生体中一个基因片段的长度应该不会少于500,000到600,000碱基对。
Accordingly, endosymbionts had never really dipped below a genomic sequence length of 500,000 to 600,000 base pairs.
形成DNA、RNA单体以及编码遗传信息的化学结构,也就是组成碱基对的碱基包括A、G、T、C、U。
The chemical structures that form the units of DNA and RNA and that encode genetic information i.e. the bases that make up the base-pairs are A, G, T, C and U (see DNA).
另外有些基因,特别是由许多相同的碱基对短片段不断重复而所组成的基因,是很难很好地测序的。
And some parts, particularly those where the same short pattern of base pairs is repeated over and over again, remain difficult to sequence well.
除了低错误率,Kedes博士还要求排序的完整性——就是说要包括至少98%的基因碱基对。
Besides the low error rate, Dr Kedes requires that the sequence be complete-meaning that it includes at least 98% of the genome's base pairs.
大多数研究人员都集中在DNA碱基对(AT和CG)的单一变化引起的致命的疾病,如囊性纤维化。
Most researchers have focused on single changes in DNA base pairs (at and CG) that cause fatal diseases, such as cystic fibrosis.
搜索的文本字符串“AGAGCTAGCTAGCT”显示地方的几十个碱基对的序列显示在人类基因组。
Searching for the text string "AGAGCTAGCTAGCT" shows the dozens of places that sequence of base pairs shows up in the human genome.
纯母乳喂养的儿童的平均端粒长度在350 - 450个DNA碱基对之间,大约比其他儿童的端粒长5%。
Average telomere length in exclusively breastfed children was between 350 and 450 DNA base pairs - or approximately 5 percent - longer than in the other children.
当柏保博士将他的拷贝数从1倍增加到20倍时,将会有大量的信息浮现出来,关键在于每一个碱基对都有代表性。
Much more information should emerge as Dr Paabo increases his one-fold coverage to 20-fold, the point at which almost every base pair is represented.
目前为止的示例都假定DNA碱基对之间不匹配的扣分应该相等-例如,认为G变异为A与变异为C的可能性相当。
The examples so far have naively assumed that the penalty for a mismatch between DNA bases should be equal - for example, that a G is as likely to mutate into an a as a c.
科学家们一直试图弄明白一大堆碱基对是如何构造出人脑这个在已知的宇宙中最复杂的机器的。这个图将为此提供宝贵的资源。
It promises to be an invaluable resource for scientists trying to figure out how a text of base pairs constructs the most complicated machine in the known universe.
科学家们先前预计人类DNA的30亿个碱基对中有多达100 000个基因;可他们惊讶地发现只有不到35 000个。
Scientists expected to find as many as 100, 000 genes packed into the 3 billion bases of human DNA; they were startled to learn that there were fewer than 35, 000.
科学家们先前预计人类DNA的30亿个碱基对中有多达100 000个基因;可他们惊讶地发现只有不到35 000个。
Scientists expected to find as many as 100, 000 genes packed into the 3 billion bases of human DNA; they were startled to learn that there were fewer than 35, 000.
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