结论盐酸托烷司琼氯化钠注射液治疗化疗药物所致恶心、呕吐安全有效。
Conclusion Tropisetron hydrochloride and sodium chloride injection is safe and effective on nausea and vomiting induced by chemotherapy.
以淀粉为主要填充剂,采用不同工艺制备盐酸托烷司琼胶囊。
The tropisetron hydrochloride capsules were prepared by different methods with starch as main excipient.
方法:以吲哚-3-甲酸为起始原料,酰氯化后与托品醇锂发生缩合反应,再与盐酸成盐制得盐酸托烷司琼。
Methods tropisetron hydrochloride was synthesized from indol-3-yl carboxylic acid by chlorination and condensation with tropic alcohol lithium, then salt formation with hydrochlororic acid.
目的:研究国产盐酸托烷司琼胶囊与进口注射液口服给药后的人体相对生物利用度。
OBJECTIVE To study the pharmacokinetics and relative bioavailability of tropisetron hydrochloride domestic capsule and imported injection in healthy volunteers.
目的合成盐酸托烷司琼并改进其合成工艺。
OBJECTIVE To synthesize Tropisetron hydrochloride and optimize the process.
以3-吲哚甲酸为起始原料,经氯化亚砜酰氯化、与托品醇缩合合成了托烷司琼盐酸盐。
Tropisetron Hydrochloride was synthesized from 1Hindol-3-carboxylic acid by chloride acetylation and condensation with Tropic alcohol.
目的研究盐酸托烷司琼胶囊的人体药动学和相对生物利用度并求证国产盐酸托烷司琼胶囊的生物等效性。
OBJECTIVE to study the pharmacokinetics and relative bioavailability of tropisetron hydrochloride capsules in healthy volunteers and to evaluate the bioequivalence.
目的研究盐酸托烷司琼胶囊的人体药动学和相对生物利用度并求证国产盐酸托烷司琼胶囊的生物等效性。
OBJECTIVE to study the pharmacokinetics and relative bioavailability of tropisetron hydrochloride capsules in healthy volunteers and to evaluate the bioequivalence.
应用推荐