显然,最重要的终点是总体生存率。
过去的数十年里,肿瘤生存率有着显著的提升。
Over the past few decades, cancer survival rates have significantly increased.
提示正确的综合治疗才能提高生存率。
It indicates only correct integrative treatment can improve survival rates.
另外,生存率很大程度上受复发的治疗选择影响。
In addition, survival is heavily influenced by the choice of treatment for recurrences.
由于明显延长生存率使早期患者获益。
Earlier stage patients benefited with significantly longer survival rates.
其中8名患者没有讨论生存率的问题。
主要终点为总体生存率。
例如,与人合住的人的生存率只比独居的人高19%。
For instance, people who lived withothers had just a 19 percent survival benefit compared with those who livedalone.
Joy Lawn说,提高新生儿生存率不仅需要钱。
Improving newborn survival rates takes more than money, says Joy Lawn.
每项研究统计了6年和21年间的步速测量和生存率。
Each study had collected walking speed measurements and survival rates dating back between six and 21 years.
小肿瘤患者(T1-T2)有极高的生存率。
生存率分析使用了Kaplan -Meier方法。
Kaplan-Meier methods were used to compute the survival analyses.
主要效果终端指标为总生存率和症状进展时间。
Primary efficacy endpoints were overall survival and time to symptomatic progression.
预后参数评估包括总生存率和肿瘤相关生产率。
The outcome parameters assessed were overall survival and tumor-related survival.
通过降低人体温度来提高病患生存率的想法其实是老调重弹了。
The idea of chilling people to promote survival is far from new.
但大多数肿瘤的发病、生存率和治疗模式都已发生了变化。
However, incidence, survival, and practice patterns have been changing for the majority of cancers.
在进行死因分析时,接受伊马替尼治疗的患者的总体生存率为88%。
The estimated overall survival rate for patients receiving Gleevec was 88% when considering deaths from all causes.
Kitahata说有理由相信早期用药治疗可以获得更高的生存率。
"There's reason to believe you would have even better survival using drugs available now," she says.
有限数目的基因和全部生存率和肝移植后无癌生存率相联系。
A limited number of genes were related to overall survival and cancer-free survival after LT.
无论如何,除了90年代初期十分高龄的患者总的生存率还是都有所提高。
However, survival has improved in all but the very oldest ages since the early 1990s.
但是直到现在,没有试验能在统计学上有力的标明它对生存率的影响。
But until now, no trials have been statistically powered to address effects on survival.
因此,替代终点如反应率和无进展生存率被普遍接受,尽管各方意识到风险所在。
Thus, surrogate endpoints like response rate and progression-free survival are commonly accepted, although all parties involved realize the risk involved.
卵巢癌生存率在最近的35年中有所提高,但长期生存率依然较低(图3.1)。
Survival for ovarian cancer has improved over the last 35 years, but long-term rates are still low (Figure 3.1).
因此,如果能够完全阻止移植后疾病复发,则能显著提高他们的生存率。
So, if you can prevent that whole post-transplantation recurrent disease, then you are going to improve survival.
相对无效的药物需要有效的抢救药物,而这可能掩盖了药物对于生存率的真正作用。
Relatively ineffective drugs will require effective salvage drugs, and this may obscure the true effects of a drug with regard to survival.
反应率通常仅限于在二期试验中,因为它已经说明与整体生存率的关系并非始终存在。
The use of response rates is usually confined to Phase II, as it has been shown that the relation to overall survival is not always present.
两组患者的5年总的生存率都接近70%以及无复发的生存率大约为62%。
In both groups, overall 5-year survival rate was approximately 70% and recurrence-free survival rate was about 62%.
本次研究表明该疗法可能会减少肿瘤治疗过程中的压力,但却不太可能会提高女性的生存率。
The study is rare because while it makes sense that therapy might ease some of the stress of cancer treatment, few studies have shown it can boost a woman's survival.
在年龄相关组中生存率曲线呈现了斜坡式的变化,显示更年轻的妇女有更好的预后(表3.2)。
There is a steep gradient in survival by age, with younger women having a better prognosis (Figure 3.2).
在年龄相关组中生存率曲线呈现了斜坡式的变化,显示更年轻的妇女有更好的预后(表3.2)。
There is a steep gradient in survival by age, with younger women having a better prognosis (Figure 3.2).
应用推荐