目的观察t细胞特异转录因子gata - 3在支气管哮喘(哮喘)小鼠肺部的表达,探讨应用白细胞介素12 (IL - 12)阻断GATA - 3表达治疗支气管哮喘的可能性。
Objective: to observe the expression of GATA-3in asthmatic mice lungs and to explore the feasibility of interleukin (IL-12) blockading GATA-3expression in treatment of bronchial asthma.
首先他们分离与DNA的启动序列特异性结合的转录因子。
First, they isolated transcription factors that were specifically bound to DNA at their promoter sites.
我们假设,联合表达神经系特异性转录因子可以直接将成纤维细胞转换成神经元细胞。
We hypothesized that combinatorial expression of neural-lineage-specific transcription factors could directly convert fibroblasts into neurons.
已报道的包括转录因子、信号通路受体、黏附因子在内的ES细胞特异性标志与ES细胞的自我更新和全能性具有密切关系。
Es cell markers reported previously including transcription factors, receptors, adhesion molecules and so on, are involved in the mechanism of self-renew and differentiation initiation of es cells.
线粒体转录终止因子蛋白的作用是与线粒体dna的特异位点结合,导致线粒体基因转录停止。
The function role of mitochondrial transcription termination factor is binding mitochondrial special DNA and leading to terminate mitochondrial gene transcription.
结果提示,在输卵管细胞中存在细胞特异性转录因子。
It is suggested that there are some of cell specific transcription factors in the primary cultured chicken oviduct cells.
顺式作用元件及其结合的转录因子有生物种类特异性。
These elements and their binding transcription factors vary with species.
转录因子NF-IL6特异地在肿瘤组织中过量表达,许多报道表明抑制它的功能对肿瘤治疗有利。
NF-IL6 is specifically overexpressed in tumor tissues. Many reports have shown that abrogation of transcriptional activation activity is useful for tumor therapy.
转录因子以组织特异性和定量的方式调节其它器官形成和发育,从而在胚胎发育过程中起主要的调节作用。
Transcription factors can regulate the expression of other genes in a tissue-specific and quantitative manner and thereby serving as major regulators of embryonic developmental processes.
对香猪、上海白猪、大约克夏猪的垂体特异性转录因子(PIT- 1)基因进行了单核苷酸多态性(snp)分析。
The single nucleotide polymorphisms (SNP) of pituitary specific transcription factor 1 (PIT-1) gene was analyzed in Xiang pig, Shanghai White pig and Yorkshire pig.
甲状腺器官形态形成早期阶段,某些转录因子通过激活甲状腺特异基因的转录,对甲状腺细胞迁移、增殖与分化起重要作用。
Genes involved at early stage of the morphogenesis play important roles in thyroid cell migration, proliferation and differentiation by activating thyroid-specific gene transcription.
本文综述了在这一领域的最新进展,以及序列特异性DNA结合转录因子和染色质重塑酶在招聘自己的角色之间的关系。
This review summarizes recent advances in this field, and the relationship between sequence-specific DNA-binding transcription factors and their roles in recruitment of chromatin remodeling enzymes.
肌细胞增强因子-2(M EF2A)是心肌细胞特异性基因表达和转录的中心调控因素。
Myocyte enhancer factor2(MEF2) is an important factor in activating muscle-specific genes expression and controlling transcription.
POU1F1蛋白是动物垂体前叶特异性表达的一种具有重要功能的特异性转录因子。
POU1F1 the protein is the animal prehypophysis specificity expression protein, is one kind of important function transcription factor.
POU1F1蛋白是动物垂体前叶特异性表达的一种具有重要功能的特异性转录因子。
POU1F1 the protein is the animal prehypophysis specificity expression protein, is one kind of important function transcription factor.
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